EFS
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Example
EFS
Donors
Matching at HLA-A,-B,-C,-DRB1:
0
1
2
3
4
5
6
7
8
Match
Mismatch
Matching at HLA-DQB1:
0
1
2
Matching at HLA-DPB1:
0
1
2
Donor CMV serostatus, pre-HCT:
Negative
Positive
Not tested
Donor type:
Related
Unrelated
Donor age:
Donor race:
Non-hispanic white
Hispanic or non-white
Donor sex:
Male
Female
Donor ABO type:
AB
O
A
B
Donor parity:
0
1+
Graft source:
Bone marrow
Peripheral blood
DPB1 permissive:
No
Yes
Matching at HLA-DQA1,-DPA1,-DRBX:
Patient
Recipient sex:
Male
Female
Disease / indication for transplant:
AML
ALL
Other leukemia
CML
MDS/MF
Other acute leukemia
NHL
HD
PCD
Solid tumor
Breast cancer
SAA
IEA
IIS
IPA
IMD
HIS
AI
Other
MPN
Refined disease risk index:
Low
Intermediate
High
Very high
TBD cytogenetics
Recipient CMV serostatus, pre-HCT:
Negative
Positive
Not tested
History of mechanical ventilation:
No
Yes
History of proven invasive fungal infection:
No
Yes
Reported planned conditioning intensity:
MAC
NMA
RIC
Recipient age:
Interval from diagnosis to transplant, months:
Recipient race:
Non-hispanic white
Hispanic or non-white
HCT-CI score:
GVHD prophylaxis (major):
Ex-vivo T-cell depletion
CD34 selection
Post-Cy
Tac based
CsA based
Other
ATG/Campath use:
No
Yes
History of malignancy:
No history
History of malignancy
Recipient ABO type:
AB
O
A
B
Karnofsky/Lansky performance score:
TBI dose groups:
No TBI used
MAC TBI - Non-fractionated >500 cGy or fractionated >800 cGy
RIC TBI - Non-fractionated 200-500 cGy or fractionated 500-800 cGy
NMA TBI - 200 cGy or less
Median household income ($) based on zipcode:
AML
MDS transformed to AML:
No
Yes
Therapy related AML:
No
Yes
Number of induction cycles to
achieve CR1 (AML):
1
N/A, disease status at HCT not in CR
3+
Cytogenetic ELN risk group for AML:
Normal
Favorable
Intermediate
Poor
APL
ALL
Cytogenetic score (ALL):
Normal
Favorable
Intermediate
Poor
Other
Ph+ (ALL):
No
Yes
ALL immunophenotype:
T-cell
B-cell
Unspecified
BCR/ABL molecular marker at last
evaluation (ALL only):
No
Yes
MDS
Therapy related (MDS/MPN):
No
Yes
IPSS-R at diagnosis (MDS):
Very low
Low
Intermediate
High
Very high
Disease risk prior to HCT (MDS):
Early
Advanced
Other
Predisposing condition (MDS/MPN):
No
Yes
IPSS-R at transplant (MDS):
Very low
Low
Intermediate
High
Very high
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